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KMID : 1100220040030010055
Dementia and Neurocognitive Disorders
2004 Volume.3 No. 1 p.55 ~ p.59
A Case with Cholinesterase Inhibitor Responsive Asymmetric Posterior Cortical Atrophy
Kim Yun-Hui

Lee Yeon-Su
Lee Jong-Keol
Han Seol-Heui
Abstract
A 55-year-old right-handed woman presented initially with mild amnestic and depressive episodes but developed slowly progressive neurobehavioral symptoms indicative of posterior cortical atrophy in ensuing years. A more detailed neurobehavioral test suggested predominant right temporo-parietal dysfunction with executive functional deficits. SPECT and MRI findings revealed rihgt unilateral temporo-parietal involvement. Cholinesterase inhibitor administration for 14 months led to amelioration of cognitive dysfunction on follow-up neuropsychologic evaluation. We suggest that cases of posterior cortical atrophy or visual variant of Alzheimer¢¥s disease may be responsive to cholinesterase inhibitor therapy.
KEYWORD
Asymmetric posterior cortical atrophy, Visuoconstructional disability, Cholinesterase inhibitor
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