KMID : 1100220040030010055
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Dementia and Neurocognitive Disorders 2004 Volume.3 No. 1 p.55 ~ p.59
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A Case with Cholinesterase Inhibitor Responsive Asymmetric Posterior Cortical Atrophy
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Kim Yun-Hui
Lee Yeon-Su Lee Jong-Keol Han Seol-Heui
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Abstract
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A 55-year-old right-handed woman presented initially with mild amnestic and depressive episodes but developed slowly progressive neurobehavioral symptoms indicative of posterior cortical atrophy in ensuing years. A more detailed neurobehavioral test suggested predominant right temporo-parietal dysfunction with executive functional deficits. SPECT and MRI findings revealed rihgt unilateral temporo-parietal involvement. Cholinesterase inhibitor administration for 14 months led to amelioration of cognitive dysfunction on follow-up neuropsychologic evaluation. We suggest that cases of posterior cortical atrophy or visual variant of Alzheimer¢¥s disease may be responsive to cholinesterase inhibitor therapy.
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KEYWORD
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Asymmetric posterior cortical atrophy, Visuoconstructional disability, Cholinesterase inhibitor
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